The farthest or most distal edge of the nail unit is the hyponychium. It is found under the free edge. The hyponychium is composed of epidermis tissue. As you know, this same tissue makes up the top layer of the nail be(ds ee Figure 1.2).
The hyponychium forms a watertight seal that prevents bacteria, fungi, viruses, etc., from attacking the nail bed. Care should be taken when manicuring under the free edge. Damage to the hyponychium can lead to infection. Once infected, the natural nail plate may lift or separate from the nail bed. It may even lead to loss of the nail plate.
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